Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | BCR | P11274 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717319 | 0.84 | PRCP (0.41) | ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL28233481 | 0.80 | — | — | |
| SCHEMBL27486701 | 0.78 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL20403500 | 0.76 | HTR1A (0.35) | — | |
| SCHEMBL6749423 | 0.74 | BCL2L1 (0.41) | ESR2ESR1ALDH1A1POLBMAPT | |
| SCHEMBL19533735 | 0.73 | CA12 (0.36) | — | |
| SCHEMBL21698306 | 0.73 | KDM4E (0.36) | ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL19142426 | 0.73 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL17876566 | 0.72 | — | — | |
| SCHEMBL16213349 | 0.71 | HTR1A (0.47) | HPGDPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1195506-C | Transdermal therapeutic system with improved stability and method for the production thereof | LOHMANN THERAPIE SYST LTS (DE) | 2005-04-06 | — | — | CN | disclosed |
| CN-1402633-A | Transdermal therapeutic system with improved stability and method for the production thereof | LOHMANN THERAPIE SYST LTS (DE) | 2003-03-12 | — | — | CN | disclosed |