Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995664 | 0.98 | NPC1 (0.41) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL27562929 | 0.98 | NPC1 (0.39) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL5995632 | 0.97 | NPC1 (0.39) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL27489120 | 0.88 | MEN1 (0.44) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL27505874 | 0.87 | CYP3A4 (0.44) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5998203 | 0.87 | USP2 (0.44) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5996517 | 0.85 | CYP3A4 (0.45) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27507492 | 0.84 | L3MBTL1 (0.47) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL27562931 | 0.82 | CA12 (0.47) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5995001 | 0.80 | TAS1R3 (0.53) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1198831-C | Organic metal monoacylalkylphosphine compound | CIBA SC HOLDING AG (CH) | 2005-04-27 | — | — | CN | disclosed |
| CN-1329005-A | Organic metal monoacylalkylphosphine compound | CIBA SC HOLDING AG (CH) | 2002-01-02 | — | — | CN | disclosed |