SCHEMBL27487582

SCHEMBL27487582

Cc1ccc(S(=O)(=O)CCC(N)N)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
CYP2C19 P33261 2/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
KMT2A Q03164 6/20 0.49
NPC1 O15118 1/20 0.49
MMP1 P03956 1/20 0.47
MMP13 P45452 1/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
CA3 P07451 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825821 0.82 ALDH1A1 (0.64) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL1752264 0.81 ALDH1A1 (0.58) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL41372 0.81 ALDH1A1 (0.82) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL31363577 0.81 ALDH1A1 (0.62) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL7584620 0.81 ALDH1A1 (0.62) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL8474920 0.79 ALDH1A1 (0.60) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL27893746 0.78 ALDH1A1 (0.58) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL14491377 0.78 ALDH1A1 (0.58) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL15304259 0.78 ALDH1A1 (0.58) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA
SCHEMBL2778514 0.78 ALDH1A1 (0.69) ALDH1A1CYP2C19CYP3A4CYP2C9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1181013-A Anti-virus triaza compounds RES FOUNDATION OF STATE UNIV O (US) 1998-05-06 CN disclosed