SCHEMBL41372

SCHEMBL41372

Cc1ccc(S(=O)(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.82
CYP2C19 P33261 2/20 0.82
CYP3A4 P08684 1/20 0.82
CYP2C9 P11712 1/20 0.82
KMT2A Q03164 6/20 0.60
NPC1 O15118 1/20 0.60
GAA P10253 1/20 0.59
MEN1 O00255 1/20 0.57
LMNA P02545 1/20 0.55
MAPT P10636 1/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA3 P07451 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
CTSK P43235 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1582969 0.90 ALDH1A1 (0.91) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL1820762 0.90 ALDH1A1 (1.00) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL11698375 0.89 ALDH1A1 (0.67) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL11695704 0.89 ALDH1A1 (0.67) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL4001371 0.88 ALDH1A1 (0.87) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL8971393 0.88 ALDH1A1 (0.87) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL8971703 0.88 ALDH1A1 (0.87) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL8970657 0.88 ALDH1A1 (0.87) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL8971430 0.88 ALDH1A1 (0.87) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL5463183 0.88 ALDH1A1 (0.87) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1135376-B1 METHOD OF PRODUCING CYCLENE SCHERING AG (DE) 2003-09-17 EP claimed
US-6156890-A Process for the production of cyclene SCHERING AKTIENGESELLSCHAFT (DE) 2000-12-05 US claimed
EP-4313156-B1 DISULFIDE-BASED PRODRUG COMPOUNDS UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2025-08-06 EP disclosed
US-20240207414-A1 DISULFIDE-BASED PRODRUG COMPOUND LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2024-06-27 US disclosed
EP-4313156-A1 DISULFIDE-BASED PRODRUG COMPOUNDS Ludwig-Maximilians-Universität München (DE) 2024-02-07 EP disclosed
WO-2022200347-A1 DISULFIDE-BASED PRODRUG COMPOUNDS LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2022-09-29 WO disclosed
US-10710968-B2 Radiolabeled erlotinib analogs and uses thereof HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2020-07-14 US disclosed
EP-3176155-B1 1,2-BIS-(4,7-DIMETHYL-1,4,7-TRIAZACYCLONON-1-YL)-ETHANE AND INTERMEDIATE FOR THE SYNTHESIS OF SAME CATEXEL LTD (GB) 2019-09-25 EP disclosed
US-20190023664-A1 RADIOLABELED ERLOTINIB ANALOGS AND USES THEREOF HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2019-01-24 US disclosed
EP-3402536-A1 RADIOLABELED ERLOTINIB ANALOGS AND USES THEREOF HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LIMITED (IL) 2018-11-21 EP disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
EP-0493601-B1 LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND IDEMITSU KOSAN CO (JP) 1996-03-20 EP disclosed
US-5425897-A Electrooptics IDEMITSU KOSAN CO., LTD. (JP) 1995-06-20 US disclosed
US-5380915-A Copolymers of polydimethylsiloxane with diene ethers IDEMITSU KOSAN CO., LTD. (JP) 1995-01-10 US disclosed
US-5281685-A Polyether pendant groups, polysiloxane repeating units IDEMITSU KOSAN CO., LTD. (JP) 1994-01-25 US disclosed
EP-0493601-A1 LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-08 EP disclosed
US-5089614-A Polysubstituted 2-morpholones THE B. F. GOODRICH COMPANY (US) 1992-02-18 US disclosed
US-4914232-A FOR POLYMERS THE B. F. GOODRICH COMPANY (US) 1990-04-03 US disclosed
US-4639365-A Gadolinium chelates as NMR contrast agents THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1987-01-27 US disclosed
US-4528370-A Polysubstituted 2-morpholones NOVEON IP HOLDINGS CORP., FORMERLY KNOWN AS PMD HOLDINGS CORP. 1985-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10710968-B2 Radiolabeled erlotinib analogs and uses thereof EGFR, KRAS, ERBB4 ALDH1A1 2112/4885CYP2C19 1733/4885CYP3A4 1588/4885
US-20240207414-A1 DISULFIDE-BASED PRODRUG COMPOUND CBS, MSR1, P4HB ALDH1A1 245/4885CYP2C19 1169/4885CYP3A4 2233/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 ALDH1A1 4014/4885CYP2C19 4263/4885CYP3A4 4760/4885
US-20190023664-A1 RADIOLABELED ERLOTINIB ANALOGS AND USES THEREOF EGFR, KRAS, ERBB4 ALDH1A1 2112/4885CYP2C19 1733/4885CYP3A4 1588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.