Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 9/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRG | P23470 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27439864 | 0.82 | SMN1; SMN2 (0.38) | RIPK1ALDH1A1RECQLPTGES2 | |
| SCHEMBL293540 | 0.80 | MMP8 (0.51) | PTPRBPTPN2PTPN1PTPRAMMP8 | |
| Ammonia Solution, Strong SCHEMBL9134412 | 0.78 | PTPRB (0.50) | PTPRBPTPN2PTPN1PTPRAMMP8 | |
| SCHEMBL11509018 | 0.77 | PTPRB (0.47) | PTPRBPTPN2PTPN1PTPRAMMP8 | |
| SCHEMBL1067474 | 0.74 | SLC6A2 (0.33) | — | |
| Carbamic Acid SCHEMBL27809934 | 0.74 | PTPRB (0.47) | PTPRBPTPN2PTPN1PTPRAMMP8 | |
| SCHEMBL1071998 | 0.74 | ESR1 (0.40) | — | |
| SCHEMBL2642315 | 0.73 | CYP4F2 (0.47) | KMT2AALDH1A1 | |
| SCHEMBL1067890 | 0.73 | PTPRB (0.41) | PTPRBALDH1A1 | |
| SCHEMBL2747599 | 0.73 | SPR (0.48) | PTPRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192739-A | N-heteroaryl-pyridinesulfonamide derivatives and their use as endothelin antagonists | ZENECA LTD (GB) | 1998-09-09 | — | — | CN | disclosed |