Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489267 | 0.84 | PTGS2 (0.59) | PTGS2PTGS1NPBWR1ALDH1A1HTT | |
| SCHEMBL27488604 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1NPBWR1PKMALDH1A1 | |
| SCHEMBL4182057 | 0.83 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL27486813 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1ALDH1A1HTTNPSR1 | |
| SCHEMBL27469590 | 0.81 | PTGS2 (0.58) | PTGS2PTGS1PKMHTTNPSR1 | |
| SCHEMBL27471090 | 0.79 | PTGS2 (0.51) | PTGS2PTGS1NPBWR1PKMHTT | |
| SCHEMBL27472456 | 0.78 | PTGS2 (0.55) | PTGS2PTGS1NPBWR1PKMALDH1A1 | |
| SCHEMBL27489275 | 0.76 | PTGS2 (0.51) | PTGS2PTGS1PKMHTTNPSR1 | |
| SCHEMBL27472459 | 0.75 | PTGS2 (0.54) | PTGS2PTGS1NPBWR1 | |
| SCHEMBL27487168 | 0.75 | PTGS2 (0.47) | PTGS2PTGS1NPBWR1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |