Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489267 | 0.86 | PTGS2 (0.59) | PTGS2PTGS1HTTNPSR1ALDH1A1 | |
| SCHEMBL4394435 | 0.85 | PTGS2 (0.54) | PTGS2PTGS1HTTNPSR1ALDH1A1 | |
| SCHEMBL27488238 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1HTTNPSR1ALDH1A1 | |
| SCHEMBL27469590 | 0.82 | PTGS2 (0.58) | PTGS2PTGS1HTTNPSR1RAB9A | |
| SCHEMBL27508689 | 0.81 | PTGS2 (0.52) | PTGS2PTGS1HTTNPSR1ALDH1A1 | |
| SCHEMBL27486813 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1HTTNPSR1ALDH1A1 | |
| SCHEMBL27488242 | 0.81 | PTGS2 (0.49) | PTGS2PTGS1HTTNPSR1ALDH1A1 | |
| SCHEMBL27471090 | 0.81 | PTGS2 (0.51) | PTGS2PTGS1HTTNPSR1RAB9A | |
| SCHEMBL4180467 | 0.80 | PTGS2 (0.54) | PTGS2PTGS1HTTNPSR1ALDH1A1 | |
| SCHEMBL27472456 | 0.80 | PTGS2 (0.55) | PTGS2PTGS1HTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |