Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 11/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27472457 | 0.94 | NPBWR1 (0.43) | NPBWR1MCHR1NPC1RAB9AATM | |
| SCHEMBL27472006 | 0.93 | NPBWR1 (0.42) | NPBWR1MCHR1NPC1RAB9AATM | |
| SCHEMBL27522821 | 0.89 | NPBWR1 (0.44) | NPBWR1MCHR1NPC1RAB9ATP53 | |
| SCHEMBL27470569 | 0.89 | SMO (0.37) | NPBWR1MCHR1GAAMAPT | |
| SCHEMBL27471091 | 0.87 | NPBWR1 (0.44) | NPBWR1MCHR1NPC1RAB9AATM | |
| SCHEMBL27522818 | 0.86 | NPC1 (0.47) | NPBWR1MCHR1NPC1RAB9AATM | |
| SCHEMBL4182886 | 0.85 | NPBWR1 (0.45) | NPBWR1MCHR1NPC1RAB9AATM | |
| SCHEMBL27555439 | 0.85 | NPBWR1 (0.45) | NPBWR1MCHR1NPC1RAB9AATM | |
| SCHEMBL4187509 | 0.84 | PTGS2 (0.50) | NPBWR1MCHR1NPC1RAB9AATM | |
| SCHEMBL27488950 | 0.83 | NPBWR1 (0.40) | NPBWR1MCHR1NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |