SCHEMBL27488248

SCHEMBL27488248

Cc1ccccc1S(=O)(=O)NC(Cc1ccccc1)C(=O)C(=O)CCl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.52
ITGAV P06756 3/20 0.51
ITGB3 P05106 1/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 1/20 0.49
MMP2 P08253 8/20 0.48
MMP9 P14780 6/20 0.48
ADAMTS4 O75173 1/20 0.48
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
HTT P42858 1/20 0.46
ADAMTS5 Q9UNA0 1/20 0.46
ITGA2 P17301 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
GAA P10253 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MMP1 P03956 1/20 0.44
MMP3 P08254 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1469951 1.00 POLB (0.52) POLBITGAVITGB3MAPTALDH1A1
SCHEMBL28675504 0.88 ITGAV (0.53) POLBITGAVITGB3MAPTALDH1A1
SCHEMBL28790956 0.85 POLB (0.56) POLBITGAVITGB3MAPTALDH1A1
SCHEMBL27175038 0.85 ITGAV (0.55) POLBITGAVITGB3MAPTALDH1A1
SCHEMBL27175046 0.85 ITGAV (0.55) POLBITGAVITGB3MAPTALDH1A1
SCHEMBL6670956 0.84 POLB (0.66) POLBITGAVITGB3MAPTALDH1A1
SCHEMBL5502394 0.84 POLB (0.66) POLBITGAVITGB3MAPTALDH1A1
SCHEMBL2213327 0.84 MMP9 (0.60) POLBMAPTALDH1A1MMP2MMP9
SCHEMBL669507 0.84 MMP9 (0.60) POLBMAPTALDH1A1MMP2MMP9
SCHEMBL27677080 0.82 POLB (0.60) POLBITGAVITGB3MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115779012-A Composition with anti-aging effect and application thereof 泽生生技股份有限公司 2023-03-14 CN disclosed
CN-1162543-C Gene encoding sulfotransferase 宝酒造株式会社 2004-08-18 CN disclosed
CN-1188806-A Gene encoding sulfotransferase TAKARA SHUZO CO (JP) 1998-07-29 CN disclosed