SCHEMBL28675504

SCHEMBL28675504

Cc1ccccc1S(=O)(=O)NC(Cc1ccccc1)C(=O)CCl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGAV P06756 3/20 0.53
POLB P06746 2/20 0.53
ITGB3 P05106 1/20 0.51
SLC1A3 P43003 1/20 0.49
SLC1A2 P43004 1/20 0.49
SLC1A1 P43005 1/20 0.49
HTT P42858 1/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
MMP2 P08253 6/20 0.47
MMP9 P14780 4/20 0.47
ADAMTS4 O75173 1/20 0.47
ITGA2 P17301 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
CTSG P08311 1/20 0.46
CMA1 P23946 1/20 0.46
ADAMTS5 Q9UNA0 1/20 0.45
CTSL P07711 1/20 0.45
CTSB P07858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27488248 0.88 POLB (0.52) ITGAVPOLBITGB3SLC1A3SLC1A2
SCHEMBL1469951 0.88 POLB (0.52) ITGAVPOLBITGB3SLC1A3SLC1A2
SCHEMBL27175046 0.87 ITGAV (0.55) ITGAVPOLBITGB3SLC1A3SLC1A2
SCHEMBL27175038 0.87 ITGAV (0.55) ITGAVPOLBITGB3SLC1A3SLC1A2
SCHEMBL6670956 0.87 POLB (0.66) ITGAVPOLBITGB3SLC1A3SLC1A2
SCHEMBL5502394 0.87 POLB (0.66) ITGAVPOLBITGB3SLC1A3SLC1A2
SCHEMBL27677080 0.85 POLB (0.60) ITGAVPOLBITGB3SLC1A3SLC1A2
Tpck SCHEMBL441444 0.82 MMP9 (0.61) POLBALDH1A1MAPTMMP2MMP9
SCHEMBL28790956 0.82 POLB (0.56) ITGAVPOLBITGB3SLC1A3SLC1A2
Tpck SCHEMBL927265 0.82 MMP9 (0.61) POLBALDH1A1MAPTMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094704-A Formulations for oral administration of active agents comprising a combination of acid-neutralizing polymer and non-polymeric material 2026-05-26 CN disclosed
CN-118109478-A DNA monoclonal antibodies targeting influenza virus 宾夕法尼亚大学理事会 2024-05-31 CN disclosed
CN-113694190-B Treatment of osteoporosis 安特拉贝欧有限公司 2024-05-07 CN disclosed
CN-117545509-A Oral delivery of oligonucleotides 四纬生物制药股份有限公司 2024-02-09 CN disclosed
CN-116850132-A Formulations of active agents for oral administration 安提拉生物有限公司 2023-10-10 CN disclosed
CN-116831977-A Formulations of active agents for oral administration 安提拉生物有限公司 2023-10-03 CN disclosed
CN-116831978-A Formulations of active agents for oral administration 安提拉生物有限公司 2023-10-03 CN disclosed
CN-113713090-B Treatment of osteoporosis 安特拉贝欧有限公司 2023-06-02 CN disclosed
CN-114949185-A Treatment of osteoporosis 安特拉贝欧有限公司 2022-08-30 CN disclosed
CN-113730556-A Treatment of osteoporosis 安特拉贝欧有限公司 2021-12-03 CN disclosed
CN-113713090-A Treatment of osteoporosis 安特拉贝欧有限公司 2021-11-30 CN disclosed
CN-113694190-A Treatment of osteoporosis 安特拉贝欧有限公司 2021-11-26 CN disclosed