Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434746 | 0.82 | IFNAR1 (0.66) | LMNASMN1; SMN2RECQLKMT2AMEN1 | |
| SCHEMBL681401 | 0.82 | IFNAR1 (0.66) | LMNASMN1; SMN2RECQLKMT2AMEN1 | |
| SCHEMBL5321295 | 0.82 | IFNAR1 (0.66) | LMNASMN1; SMN2RECQLKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1093699 | 0.81 | IFNAR1 (0.64) | LMNASMN1; SMN2RECQLKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6251238 | 0.81 | IFNAR1 (0.64) | LMNASMN1; SMN2RECQLKMT2AMEN1 | |
| Isophthalic Acid SCHEMBL27656644 | 0.80 | TDP1 (0.53) | POLBKMT2AMEN1CTNNB1TDP1 | |
| Isophthalic Acid SCHEMBL27280135 | 0.77 | KMT2A (0.63) | POLBKMT2AMEN1MAPTKDM4E | |
| Isophthalic Acid SCHEMBL27285729 | 0.76 | KMT2A (0.62) | POLBKMT2AMEN1MAPTKDM4E | |
| SCHEMBL3817884 | 0.75 | CA2 (0.70) | KMT2AMEN1MAPTCTNNB1TDP1 | |
| Isophthalic Acid SCHEMBL27484405 | 0.75 | CA12 (0.64) | KMT2AMEN1TDP1MRGPRX4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1197860-C | FAB I inhibitors | SMITHKLINE BEECHAM CORP (CA) | 2005-04-20 | — | — | CN | disclosed |
| CN-1378542-A | Antigen binding fragment I inhibitors | SMITHKLINE BEECHAM CORP (US) | 2002-11-06 | — | — | CN | disclosed |