⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398950 | 0.80 | LMNA (0.33) | — | |
| SCHEMBL7440029 | 0.79 | HSD11B1 (0.36) | — | |
| SCHEMBL28893876 | 0.78 | SLC6A2 (0.33) | — | |
| SCHEMBL6027307 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL28591044 | 0.76 | KDM1A (0.37) | — | |
| SCHEMBL447640 | 0.75 | TSHR (0.31) | — | |
| SCHEMBL10444977 | 0.75 | RAD52 (0.32) | — | |
| SCHEMBL28424220 | 0.75 | SLC6A2 (0.34) | — | |
| SCHEMBL28718581 | 0.75 | — | — | |
| SCHEMBL9724884 | 0.75 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178906-C | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ���Ͽع�����˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1261876-A | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ABBOTT LAB (US) | 2000-08-02 | — | — | CN | disclosed |