Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.62 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.62 |
| ▸ | FYN | P06241 | 8/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2750800 | 0.92 | PRKD3 (0.54) | PRKD3PRKD1PRKD2FYNMAP4K4 | |
| SCHEMBL2748397 | 0.91 | PRKD3 (0.53) | PRKD3PRKD1PRKD2FYNMAP4K4 | |
| SCHEMBL2749016 | 0.90 | FYN (0.51) | PRKD3PRKD1PRKD2FYNMAP4K4 | |
| SCHEMBL2748849 | 0.86 | CDK8 (0.50) | FYNMAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL2750376 | 0.86 | ATR (0.54) | PRKD3PRKD1PRKD2FYNMAP4K4 | |
| SCHEMBL1678628 | 0.85 | PRKD3 (0.63) | PRKD3PRKD1PRKD2FYNMAP4K4 | |
| SCHEMBL1679117 | 0.84 | PRKD3 (0.71) | PRKD3PRKD1PRKD2FYNMAP4K4 | |
| SCHEMBL2748893 | 0.84 | MKNK2 (0.64) | FYNMAP4K4CDK1CDK2MKNK1 | |
| SCHEMBL2748293 | 0.83 | GRK5 (0.53) | FYNMAP4K4GRK5RAB9AHPGD | |
| SCHEMBL1679743 | 0.82 | PRKD3 (0.74) | PRKD3PRKD1PRKD2FYNMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178668-B2 | 2-aminopyridine kinase inhibitors | OSI Pharmaceuticals, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20090197862-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI PHARMACEUTICALS, INC. | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197862-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | ERBB2, ABL2, TIE1 | PRKD3 199/4885PRKD1 117/4885PRKD2 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.