Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224632 | 0.98 | MEN1 (0.64) | MEN1KMT2ATDP1HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL7823186 | 0.96 | MEN1 (0.61) | MEN1KMT2ATDP1HDAC3HDAC1 | |
| SCHEMBL3669498 | 0.90 | ALDH1A1 (0.56) | MEN1KMT2ATDP1HDAC3HDAC1 | |
| SCHEMBL5939323 | 0.87 | S1PR1 (0.64) | HDAC1GAAALDH1A1S1PR1FFAR1 | |
| SCHEMBL864629 | 0.86 | HDAC3 (0.65) | MEN1KMT2ATDP1HDAC3HDAC1 | |
| Ether SCHEMBL911373 | 0.86 | SMN1; SMN2 (0.51) | MEN1KMT2ATDP1HDAC3HDAC1 | |
| SCHEMBL11300014 | 0.85 | MEN1 (0.48) | MEN1KMT2ATDP1HDAC3HDAC1 | |
| SCHEMBL8905341 | 0.85 | HDAC3 (0.73) | MEN1KMT2ATDP1HDAC3HDAC1 | |
| SCHEMBL1981483 | 0.84 | MEN1 (0.68) | MEN1KMT2ATDP1HDAC3HDAC1 | |
| Ammonia Solution, Strong SCHEMBL27486735 | 0.83 | MEN1 (0.54) | MEN1KMT2ATDP1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229330-C | N-arylating method using amino-acid as additives | SHANGHAI INST ORGANIC CHEM (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-1203040-C | Method for synthesizing diaryl ether by using amino acid as additive | SHANGHAI INST ORGANIC CHEM (CN) | 2005-05-25 | — | — | CN | claimed |
| CN-1462735-A | Method for synthesizing diaryl ether by using amino acid as additive | SHANGHAI INST ORGANIC CHEM (CN) | 2003-12-24 | — | — | CN | claimed |
| CN-1450049-A | N-arylating method using amino-acid as additives | SHANGHAI INST ORGANIC CHEM (CN) | 2003-10-22 | — | — | CN | claimed |
| CN-1229330-C | N-arylating method using amino-acid as additives | SHANGHAI INST ORGANIC CHEM (CN) | 2005-11-30 | — | — | CN | disclosed |
| CN-1203040-C | Method for synthesizing diaryl ether by using amino acid as additive | SHANGHAI INST ORGANIC CHEM (CN) | 2005-05-25 | — | — | CN | disclosed |
| CN-1462735-A | Method for synthesizing diaryl ether by using amino acid as additive | SHANGHAI INST ORGANIC CHEM (CN) | 2003-12-24 | — | — | CN | disclosed |
| CN-1450049-A | N-arylating method using amino-acid as additives | SHANGHAI INST ORGANIC CHEM (CN) | 2003-10-22 | — | — | CN | disclosed |