Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.73 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204842 | 0.98 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL11775902 | 0.98 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL28329735 | 0.98 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| Hydrochloric Acid SCHEMBL3229769 | 0.96 | HDAC3 (0.71) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL864629 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL2224632 | 0.86 | MEN1 (0.64) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL15694807 | 0.86 | ALDH1A1 (0.67) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| Ammonia Solution, Strong SCHEMBL27489178 | 0.85 | MEN1 (0.61) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| Hydrochloric Acid SCHEMBL7823186 | 0.85 | MEN1 (0.61) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL18939229 | 0.84 | ALDH1A1 (0.97) | HDAC3HDAC1HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106574202-A | basic ashless additive | 路博润公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-102746175-B | Substituted pyrimidodiazepines useful as PLK1 inhibitors | TAKAEDA CHEMICAL IND LTD | 2014-01-15 | — | — | CN | disclosed |
| CN-102746175-A | Substituted pyrimidodiazepines useful as PLK1 inhibitors | HOFFMANN LA ROCHE | 2012-10-24 | — | — | CN | disclosed |
| CN-102712640-A | Tricyclic heterocyclic compounds, compositions and methods of use thereof | HOFFMANN LA ROCHE | 2012-10-03 | — | — | CN | disclosed |
| CN-101636399-B | Substituted pyrimidodiazepines useful as PLK1 inhibitors | HOFFMANN LA ROCHE CH | 2012-04-18 | — | — | CN | disclosed |
| CN-101636399-A | Substituted pyrimido diazepines useful as PLK1 inhibitors | HOFFMANN LA ROCHE | 2010-01-27 | — | — | CN | disclosed |
| CN-101090888-A | 4-aminopiperidine derivatives | HOFFMANN LA ROCHE (CH) | 2007-12-19 | — | — | CN | disclosed |
| US-5703125-A | MELT BLEND OF SOAP, SURFACTANT AND SOLVENT | G. D. SEARLE & CO. (US) | 1997-12-30 | — | — | US | disclosed |