Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7441898 | 0.85 | REN (0.67) | RENKCNH2 | |
| Tert-Butyl Formate SCHEMBL27489233 | 0.82 | REN (0.59) | RENKCNH2 | |
| SCHEMBL6959341 | 0.81 | REN (0.77) | REN | |
| SCHEMBL6041668 | 0.81 | REN (0.80) | REN | |
| SCHEMBL6042521 | 0.81 | REN (0.80) | REN | |
| SCHEMBL6043623 | 0.81 | REN (0.80) | REN | |
| SCHEMBL6043786 | 0.81 | REN (0.82) | REN | |
| Hydrochloric Acid SCHEMBL6041978 | 0.81 | REN (0.76) | REN | |
| SCHEMBL6958926 | 0.79 | REN (0.80) | REN | |
| SCHEMBL6959228 | 0.79 | REN (0.63) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1256326-C | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | CN | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |