SCHEMBL6959228

SCHEMBL6959228

COC(O[C@H]1CNC[C@@H](O)[C@@H]1c1ccc(OCCCOCc2ccccc2)cc1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6041878 0.89 REN (0.59) REN
SCHEMBL27504321 0.89 REN (0.59) REN
SCHEMBL6041668 0.82 REN (0.80) REN
SCHEMBL6042521 0.82 REN (0.80) REN
SCHEMBL6041431 0.82 REN (0.56) REN
SCHEMBL6042701 0.82 REN (0.79) REN
SCHEMBL6959226 0.81 REN (0.69) REN
SCHEMBL6043623 0.80 REN (0.80) REN
Bicarbonate SCHEMBL7441898 0.80 REN (0.67) REN
SCHEMBL6042303 0.80 REN (0.61) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP claimed