SCHEMBL27489592

SCHEMBL27489592

CCCCC1=C([Zr](Cc2ccccc2)Cc2ccccc2)CC=C1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.34
DNM1 Q05193 2/20 0.33
HTR2A P28223 1/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
HTT P42858 2/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28350421 0.88 KCNH2 (0.35) SIGMAR1DNM1POLBMEN1KMT2A
SCHEMBL28338388 0.78 HTR2A (0.35) SIGMAR1HTR2APOLB
SCHEMBL9353284 0.74
SCHEMBL27463486 0.73 TSHR (0.34)
SCHEMBL3861600 0.73 SIGMAR1 (0.39) SIGMAR1DNM1HTR2APOLBMEN1
SCHEMBL7150370 0.73
SCHEMBL27542253 0.72
SCHEMBL4465789 0.72 SIGMAR1 (0.38) SIGMAR1DNM1HTR2APOLBMEN1
SCHEMBL299733 0.72 SIGMAR1 (0.38) SIGMAR1DNM1HTR2APOLBMEN1
SCHEMBL27345874 0.71 GBA1 (0.34) SIGMAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1152062-C Olefin solution polymerization �Ϻ���ͨ��ѧ 2004-06-02 CN disclosed
CN-1120849-C Highly soluble olefin polymerization catalyst activators DOW GLOBAL TECHNOLOGY CO (US) 2003-09-10 CN disclosed
CN-1334845-A Hot melt adhesive polypropylene/ethylene polymer fibers and compositions for making the same DOW CHEMICAL CO (US) 2002-02-06 CN disclosed
CN-1219178-A Olefin solution polymerization DOW CHEMICAL CO (US) 1999-06-09 CN disclosed
CN-1214698-A Solution polymerization process with dispersed catalyst activator DOW CHEMICAL CO (US) 1999-04-21 CN disclosed
CN-1214699-A Highly soluble olefin polymerization catalyst activator DOW CHEMICAL CO (US) 1999-04-21 CN disclosed