SCHEMBL299733

SCHEMBL299733

CCCCC1=C([Hf]C2=C(CCCC)C=CC2)CC=C1.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.38
KCNH2 Q12809 2/20 0.36
ORAI1 Q96D31 1/20 0.35
ORAI2 Q96SN7 1/20 0.35
ORAI3 Q9BRQ5 1/20 0.35
TRPV6 Q9H1D0 1/20 0.35
TLR8 Q9NR97 1/20 0.35
DNM1 Q05193 1/20 0.34
HSD11B1 P28845 1/20 0.34
CETP P11597 1/20 0.34
HTR2A P28223 1/20 0.34
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 1/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL8155712 0.87 TSHR (0.32) SIGMAR1SMN1; SMN2SLC6A3POLB
Fluoride SCHEMBL1131141 0.86 HTR2A (0.39) SIGMAR1HTR2AMAPK1SMN1; SMN2ADRA1A
Fluoride SCHEMBL1130344 0.85
Hydrochloric Acid SCHEMBL3898494 0.85
SCHEMBL6066857 0.85
Hydrochloric Acid SCHEMBL3353879 0.85
SCHEMBL2160061 0.84
SCHEMBL618875 0.84
Methoxymethane SCHEMBL28432174 0.84
SCHEMBL620800 0.82 ACHE (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285896-B1 High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom BOREALIS AG (AT) 2016-09-07 EP claimed
EP-1802670-B1 LINEAR LOW DENSITY POLYETHYLENE, PROCESS FOR THE PREPARATION THEREOF AND FILMS MADE THEREFROM BOREALIS TECH OY (FI) 2013-12-04 EP claimed
US-8476370-B2 High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom BOREALIS AG (AT) 2013-07-02 US claimed
US-20110274860-A2 High Density Polymer Compositions, A Method for Their Preparation and Pressure-Resistant Pipes made Therefrom BOREALIS AG (AT) 2011-11-10 US claimed
US-20110165357-A1 High Density Polymer Compositions, A Method for Their Preparation and Pressure-Resistant Pipes made Therefrom BOREALIS AG (AT) 2011-07-07 US claimed
EP-2285896-A1 HIGH DENSITY POLYMER COMPOSITIONS, A METHOD FOR THEIR PREPARATION AND PRESSURE-RESISTANT PIPES MADE THEREFROM Borealis AG (AT) 2011-02-23 EP claimed
WO-2009147022-A1 HIGH DENSITY POLYMER COMPOSITIONS, A METHOD FOR THEIR PREPARATION AND PRESSURE-RESISTANT PIPES MADE THEREFROM BOREALIS AG (AT) 2009-12-10 WO claimed
EP-2130863-A1 High density polymer compositions, a method for their preparation and pressure-resistant pipes made therefrom Borealis AG (AT) 2009-12-09 EP claimed
EP-1802670-A1 LINEAR LOW DENSITY POLYETHYLENE, PROCESS FOR THE PREPARATION THEREOF AND FILMS MADE THEREFROM Borealis Technology Oy (FI) 2007-07-04 EP claimed
WO-2006045501-A1 LINEAR LOW DENSITY POLYETHYLENE, PROCESS FOR THE PREPARATION THEREOF AND FILMS MADE THEREFROM BOREALIS TECHNOLOGY OY (FI) 2006-05-04 WO claimed
US-20240071647-A1 COMPOSITION BOREALIS AG (AT) 2024-02-29 US disclosed
CN-117597388-A Polyethylene for producing crosslinked Polyethylene (PEX) 北欧化工公司 2024-02-23 CN disclosed
WO-2023247478-A1 POLYETHYLENE COPOLYMER FOR A FILM LAYER BOREALIS AG (AT) 2023-12-28 WO disclosed
EP-4296289-A1 POLYETHYLENE COPOLYMER FOR A FILM LAYER Borealis AG (AT) 2023-12-27 EP disclosed
EP-4275217-A1 COMPOSITION Borealis AG (AT) 2023-11-15 EP disclosed
WO-2007045415-A1 COMPOSITION BOREALIS TECHNOLOGY OY (FI) 2007-04-26 WO disclosed
US-20070037932-A1 Nucleating agent BOREALIS TECHNOLOGY OY (FI) 2007-02-15 US disclosed
WO-2006045501-A1 LINEAR LOW DENSITY POLYETHYLENE, PROCESS FOR THE PREPARATION THEREOF AND FILMS MADE THEREFROM BOREALIS TECHNOLOGY OY (FI) 2006-05-04 WO disclosed
WO-2006045550-A1 COMPOSITION BOREALIS TECHNOLOGY OY (FI) 2006-05-04 WO disclosed
EP-1574772-A1 A crosslinked ethylene polymer pressure pipe and a method for the preparation thereof Borealis Technology Oy (FI) 2005-09-14 EP disclosed