Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504434 | 0.80 | TDP1 (0.46) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL27665248 | 0.80 | TDP1 (0.46) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL3870922 | 0.79 | LMNA (0.41) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL27783809 | 0.78 | TDP1 (0.44) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL23996151 | 0.77 | MEN1 (0.42) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL28378861 | 0.77 | MEN1 (0.42) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL27689592 | 0.77 | MEN1 (0.42) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL19923136 | 0.77 | GLA (0.55) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL58005 | 0.77 | GLA (0.55) | GLATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL2985370 | 0.77 | GLA (0.55) | GLATDP1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1134434-C | Novel 2-heterocyclic substituted dihydropyrimidines | 先灵公司 | 2004-01-14 | — | — | CN | disclosed |
| CN-1297449-A | Novel 2-heterocyclic substituted dihydropyrimidines | BAYER AG (DE) | 2001-05-30 | — | — | CN | disclosed |