SCHEMBL3870922

SCHEMBL3870922

O=C(OC=Cc1ccccc1)C(Cl)CC(Cl)C(=O)OC=Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
PAM P19021 2/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP1A2 P05177 2/20 0.40
HDAC3 O15379 2/20 0.40
HDAC4 P56524 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
PLIN1 O60240 2/20 0.40
MAPT P10636 2/20 0.40
RECQL P46063 2/20 0.40
PLIN5 Q00G26 2/20 0.40
ABHD5 Q8WTS1 2/20 0.40
TNKS O95271 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27489772 0.79 GLA (0.44) LMNAPAMALDH1A1CYP1A2HDAC3
SCHEMBL27665248 0.77 TDP1 (0.46) LMNAPAMALDH1A1CYP1A2HDAC3
SCHEMBL14504434 0.77 TDP1 (0.46) LMNAPAMALDH1A1CYP1A2HDAC3
SCHEMBL27783809 0.76 TDP1 (0.44) LMNAPAMALDH1A1CYP1A2HDAC3
SCHEMBL23996151 0.75 MEN1 (0.42) LMNAPAMALDH1A1CYP1A2HDAC3
SCHEMBL28378861 0.75 MEN1 (0.42) LMNAPAMALDH1A1CYP1A2HDAC3
SCHEMBL27689592 0.75 MEN1 (0.42) LMNAPAMALDH1A1CYP1A2HDAC3
SCHEMBL6510327 0.75 HTR2A (0.43) LMNAALDH1A1CYP1A2HDAC3HDAC4
SCHEMBL6555184 0.74 HDAC1 (0.48) LMNAPAMALDH1A1CYP1A2HDAC3
SCHEMBL28747103 0.74 HDAC1 (0.48) LMNAPAMALDH1A1CYP1A2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130196144-A1 Laser Engraveable Compositions for Relief Image Printing Elements NAPP SYSTEMS, INC. 2013-08-01 US disclosed
US-7625959-B2 Curable jettable liquid for flexography AGFA GRAPHICS, N.V. (BE) 2009-12-01 US disclosed
EP-1637322-B1 Method for manufacturing a flexographic printing master AGFA GRAPHICS NV (BE) 2009-05-13 EP disclosed
EP-1637926-B1 Curable jettable liquid for the production of a flexographic printing plate AGFA GRAPHICS NV (BE) 2009-04-22 EP disclosed
US-7401552-B2 Method for manufacturing a flexographic printing master AGFA GRAPHICS N.V. (BE) 2008-07-22 US disclosed
US-20060073417-A1 Photopolymer plate and method for imaging the surface of a photopolymer plate HERMESDORF MARK 2006-04-06 US disclosed
EP-1637926-A2 Curable jettable liquid for the production of a flexographic printing plate Agfa-Gevaert (BE) 2006-03-22 EP disclosed
EP-1637322-A2 Method for manufacturing a flexographic printing master Agfa-Gevaert (BE) 2006-03-22 EP disclosed
US-20060055761-A1 Method for manufacturing a flexographic printing master AGFA-GEVAERT (BE) 2006-03-16 US disclosed
US-20060054040-A1 Curable jettable liquid for flexography AGFA-GEVAERT (BE) 2006-03-16 US disclosed
US-5073791-A IMAGE FORMING DEVICE CANON KABUSHIKI KAISHA (JP) 1991-12-17 US disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
EP-0453317-A2 Image forming medium CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0410803-A2 Image forming device CANON KABUSHIKI KAISHA (JP) 1991-01-30 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed
EP-0353030-A2 Photopolymerization initiator and photosensitive composition employing the same CANON KABUSHIKI KAISHA (JP) 1990-01-31 EP disclosed
EP-0332455-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed
EP-0297583-A2 Photosensitive material and image forming method by use thereof CANON KABUSHIKI KAISHA (JP) 1989-01-04 EP disclosed