SCHEMBL27489807

SCHEMBL27489807

CC(=O)OCCC1(C[N+](=O)[O-])CCC1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
GALR3 O60755 2/20 0.32
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
CHRNB2 P17787 1/20 0.32
TBXA2R P21731 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRNA10 Q9GZZ6 1/20 0.32
CHRNA9 Q9UGM1 1/20 0.32
TSHR P16473 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29861012 0.88 ALDH1A1 (0.31) ALDH1A1GALR3CHRM5CHRM1CHRM3
SCHEMBL28839404 0.86 ALDH1A1 (0.30) ALDH1A1
SCHEMBL29860797 0.86 HTT (0.31) ALDH1A1HTT
SCHEMBL27466851 0.83 ALDH1A1 (0.30) ALDH1A1
SCHEMBL27637715 0.81 HTT (0.32) ALDH1A1GALR3CHRM5CHRM1CHRM3
SCHEMBL27543877 0.81 HTT (0.32) ALDH1A1GALR3CHRM5CHRM1CHRM3
SCHEMBL25277676 0.74 CYP1A2 (0.30)
SCHEMBL1697992 0.72 ALOX15 (0.39) ALDH1A1GALR3CHRM5CHRM1CHRM3
SCHEMBL5692021 0.72 GAA (0.36) ALDH1A1SMN1; SMN2GAA
SCHEMBL31289958 0.72 ALDH1A1 (0.33) ALDH1A1GALR3CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907365-B Influenza virus inhibitor and application thereof 扬子江药业集团有限公司 2023-12-01 CN disclosed
CN-117120441-A Influenza virus inhibitor and application thereof 扬子江药业集团有限公司 2023-11-24 CN disclosed
WO-2022171198-A1 INFLUENZA VIRUS INHIBITOR AND USE THEREOF 扬子江药业集团有限公司 2022-08-18 WO disclosed
CN-114907365-A Influenza virus inhibitor and application thereof 扬子江药业集团有限公司 2022-08-16 CN disclosed
CN-100367946-C Gabapentin analogs for the treatment of fibromyalgia and other disorders WARNER LAMBERT CO (US) 2008-02-13 CN disclosed
CN-1303059-C Cyclic amino acids and derivatives thereof useful as pharmaceutical agents WARNER LAMBERT CO (US) 2007-03-07 CN disclosed
CN-1720038-A Gabapentin analogs for the treatment of fibromyalgia and other disorders WARNER LAMBERT CO (US) 2006-01-11 CN disclosed
CN-1500773-A Cyclic amino acids and derivatives thereof useful as pharmaceutical agents ��ʲ 2004-06-02 CN disclosed
CN-1138755-C Cyclic amino acids and derivatives thereof as pharmaceuticals ��ʲ 2004-02-18 CN disclosed
CN-1276784-A Cyclic amino acids and their organisms as medicaments WARNER LAMBERT CO (US) 2000-12-13 CN disclosed