Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491081 | 0.68 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL7677302 | 0.67 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL10300269 | 0.67 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL3007986 | 0.67 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL2376239 | 0.65 | ENPP2 (0.72) | PTGS2 | |
| SCHEMBL28740843 | 0.65 | ENPP2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL12473624 | 0.64 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL4715345 | 0.64 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL5361952 | 0.63 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL29402246 | 0.63 | PTGS2 (0.43) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192900-A | 2-(3,5-dieluorophenyl)-3-(4-(methylsulfonyl) phenyl)-2-cyclopenten-1-one useful as inhibitor of COX-2 | MERCK FROSST CANADA INC (CA) | 1998-09-16 | — | — | CN | claimed |