Acetic Acid Methyl Ester

Acetic Acid Methyl Ester

SCHEMBL27490346

COC(C)=O.OCC1CC1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
NR1H2 P55055 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 3/20 0.33
ESR1 P03372 1/20 0.33
CYP2C9 P11712 1/20 0.33
ESR2 Q92731 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 2/20 0.32
ALOX5 P09917 1/20 0.32
ALOX15 P16050 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
EPHX2 P34913 1/20 0.30
BRD4 O60885 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL9562373 0.84
Acetic Acid SCHEMBL2479593 0.81
Methoxymethane SCHEMBL10787753 0.81 ESR1 (0.39) NR1H2CYP3A4ESR1CYP2C9ESR2
SCHEMBL28529026 0.79 BRD4 (0.44) ALDH1A1NR1H2MGAMGAASI
SCHEMBL351398 0.79 TP53 (0.44) ALDH1A1GAA
SCHEMBL22856596 0.79 LMNA (0.37) ALDH1A1NR1H2LMNAHSD17B10
SCHEMBL7186641 0.79 LMNA (0.37) ALDH1A1NR1H2LMNAHSD17B10
SCHEMBL351399 0.79 TP53 (0.44) ALDH1A1GAA
SCHEMBL408809 0.79 TP53 (0.44) ALDH1A1GAA
Acetic Acid Methyl Ester SCHEMBL594991 0.78 ALDH1A1 (0.48) ALDH1A1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819300-B Preparation method of 2- (1- (mercaptomethyl) cyclopropyl) acetic acid 江苏阿尔法集团盛基药业(宿迁)有限公司 2024-10-25 CN disclosed
CN-115819300-A Preparation method of 2 (1- (mercapto) cyclopropyl) acetic acid 宿迁盛基医药科技有限公司 2023-03-21 CN disclosed
CN-1209809-A Noval chemical compound FUJISAWA PHARMACEUTICAL CO (JP) 1999-03-03 CN disclosed