Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593796 | 0.86 | CYP11B1 (0.58) | TLR8ALDH1A1CNR2CYP11B1CYP11B2 | |
| SCHEMBL1502180 | 0.78 | IDO1 (0.49) | ICMTCYP11B1CYP11B2IDO1 | |
| SCHEMBL27984310 | 0.78 | CYP11B1 (0.51) | TLR8ALDH1A1CYP2C19CYP1A2CNR2 | |
| SCHEMBL7683890 | 0.78 | CYP2A6 (0.43) | TLR8CYP2A6ALDH1A1CYP2A13CYP2C9 | |
| SCHEMBL10983627 | 0.77 | IDO1 (0.44) | ALDH1A1CYP3A4HIF1AHSD17B10CYP11B1 | |
| SCHEMBL15653534 | 0.77 | CYP11B1 (0.54) | TLR8ALDH1A1CNR2CYP11B1CYP11B2 | |
| SCHEMBL20409162 | 0.77 | ADORA2A (0.38) | TLR8ALDH1A1ICMTCYP11B1CYP11B2 | |
| SCHEMBL1502091 | 0.76 | CYP11B1 (0.62) | ALDH1A1CYP3A4CYP2D6CYP1A2CYP11B1 | |
| SCHEMBL31627317 | 0.75 | CYP2A6 (0.62) | CYP2A6ALDH1A1CYP2A13CYP2C9CYP2C19 | |
| SCHEMBL1133225 | 0.75 | CYP2A6 (0.62) | CYP2A6ALDH1A1CYP2A13CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1211385-C | Bicyclic imidazo-5-yl-amine derivs. | GRUENENTHAL GMBH (DE) | 2005-07-20 | — | — | CN | disclosed |
| CN-1402726-A | Bicyclic imidazo-5-yl-amine derivs. | GRUENENTHAL GMBH (DE) | 2003-03-12 | — | — | CN | disclosed |