Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27509754 | 0.84 | SLC2A1 (0.35) | AR | |
| SCHEMBL28069973 | 0.82 | SIRT2 (0.33) | — | |
| SCHEMBL29222600 | 0.75 | ADRA2A (0.47) | — | |
| SCHEMBL5158063 | 0.75 | PTGDR2 (0.39) | P2RX7AKR1B1 | |
| SCHEMBL27466286 | 0.75 | — | — | |
| SCHEMBL29222608 | 0.72 | MAP3K14 (0.47) | — | |
| SCHEMBL27757459 | 0.71 | MAP3K14 (0.34) | — | |
| SCHEMBL6340390 | 0.71 | CNR1 (0.34) | AR | |
| SCHEMBL29222712 | 0.69 | ADRA2A (0.47) | P2RX7 | |
| SCHEMBL27489452 | 0.68 | PTGS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1205187-C | New amidino derivatives and their use as thrombin inhibitors | ASTRA AB (SE) | 2005-06-08 | — | — | CN | disclosed |
| CN-1266427-A | Amidino derivatives and their use as thrombin inhibitors | ASTRA AB (SE) | 2000-09-13 | — | — | CN | disclosed |