Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 18/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595646 | 0.94 | CCR5 (0.34) | CCR5KCNH2CCR2 | |
| SCHEMBL27492228 | 0.90 | CCR5 (0.32) | CCR5KCNH2CYP2D6 | |
| SCHEMBL27512076 | 0.90 | CCR5 (0.32) | CCR5KCNH2CYP2D6 | |
| SCHEMBL27473817 | 0.88 | CYP2D6 (0.33) | CCR5KCNH2CYP2D6 | |
| SCHEMBL27491173 | 0.88 | CYP2D6 (0.37) | CCR5KCNH2CYP2D6 | |
| SCHEMBL27492586 | 0.87 | CYP2D6 (0.34) | CCR5KCNH2CYP2D6 | |
| SCHEMBL27490108 | 0.85 | CYP3A4 (0.31) | KCNH2CYP2D6 | |
| SCHEMBL4873767 | 0.82 | NMT1 (0.33) | CCR5KCNH2CYP2D6CCR2 | |
| SCHEMBL27524127 | 0.81 | CCR5 (0.30) | CCR5KCNH2CYP2D6 | |
| SCHEMBL4876433 | 0.79 | CCR2 (0.33) | CCR5KCNH2CYP2D6CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178922-C | Substituted 1-aminoalkyllactam compounds and their use as muscarinic receptor antagonists | - | 2004-12-08 | — | — | CN | disclosed |
| CN-1430610-A | Substituted 1-aminoalkyllactam compounds and their use as muscarinic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2003-07-16 | — | — | CN | disclosed |