Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27492242 | 0.85 | CA9 (0.50) | ALDH1A1MAPTHSD17B10KDM4ETSHR | |
| SCHEMBL24109370 | 0.84 | CARM1 (0.50) | ALDH1A1MAPTHSD17B10KDM4ETSHR | |
| SCHEMBL20178641 | 0.83 | ALDH1A1 (0.51) | ALDH1A1ITGB3ITGA2BPOLBMEN1 | |
| SCHEMBL7788367 | 0.83 | ITGB3 (0.58) | ALDH1A1KDM4ECD274ITGB3ITGA2B | |
| SCHEMBL7128888 | 0.82 | ESR1 (0.51) | ALDH1A1MAPTKDM4ECD274MEN1 | |
| SCHEMBL7399072 | 0.81 | MAPT (0.61) | ALDH1A1MAPTHSD17B10KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL8824760 | 0.80 | MAPT (0.60) | ALDH1A1MAPTHSD17B10KDM4ETSHR | |
| SCHEMBL3604547 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7299565 | 0.79 | NR1H2 (0.44) | ALDH1A1MAPTHSD17B10KDM4ETSHR | |
| SCHEMBL3910177 | 0.79 | NR1H2 (0.49) | ALDH1A1MAPTHSD17B10KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1209063-A | Vitronection receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-02-24 | — | — | CN | disclosed |
| CN-1209060-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-02-24 | — | — | CN | disclosed |