Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14326984 | 0.81 | RXRA (0.51) | NPC1RAB9ACYP1A2CYP3A4HPGD | |
| SCHEMBL7594827 | 0.79 | KMT2A (0.56) | KMT2AMEN1NPC1RAB9ACYP1A2 | |
| SCHEMBL7840693 | 0.78 | KDM4E (0.57) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL23529671 | 0.77 | PTPRF (0.56) | KMT2AMEN1CYP1A2CYP3A4HPGD | |
| Bromide SCHEMBL11670771 | 0.77 | KDM4E (0.56) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL11669913 | 0.77 | KDM4E (0.56) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL4626588 | 0.76 | RXRA (0.48) | NPC1RAB9ACYP1A2CYP3A4HPGD | |
| SCHEMBL12569397 | 0.76 | RXRA (0.48) | NPC1RAB9ACYP1A2CYP3A4HPGD | |
| SCHEMBL27511068 | 0.76 | RXRA (0.48) | NPC1RAB9ACYP1A2CYP3A4HPGD | |
| SCHEMBL27892567 | 0.76 | RXRA (0.48) | NPC1RAB9ACYP1A2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161337-C | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1221738-A | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-07-07 | — | — | CN | disclosed |