Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.77 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.77 |
| ▸ | NQO2 | P16083 | 9/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043404 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL30449793 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5341583 | 0.86 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL27436070 | 0.85 | NQO2 (0.73) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL7098615 | 0.85 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL5345535 | 0.85 | NQO2 (0.73) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL5340676 | 0.84 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL5349352 | 0.83 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5343899 | 0.83 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL9126868 | 0.83 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2TRPV1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1181050-C | Novel substituted dimeric compounds, its preparing process and medicinal compsns. containing same | ɪά��ʵ���� | 2004-12-22 | — | — | CN | disclosed |