Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 15/20 | 1.00 |
| ▸ | NQO2 | P16083 | 8/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449793 | 1.00 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5334577 | 0.92 | MTNR1A (0.85) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL7016328 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL27490705 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL29032153 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL7098615 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL13523854 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1688124 | 0.86 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5349352 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9126868 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046833-A2 | IMPROVED PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2016-03-31 | — | — | WO | claimed |
| EP-2909166-A1 | PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES | Symed Labs Limited (IN) | 2015-08-26 | — | — | EP | claimed |
| WO-2014064706-A1 | PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2014-05-01 | — | — | WO | claimed |
| EP-0562956-B1 | Naphtylalkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-09-27 | — | — | EP | claimed |
| US-5420158-A | Melatonin activity | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | claimed |
| EP-0562956-A1 | Naphtylalkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-09-29 | — | — | EP | claimed |
| CN-116249691-A | Bicyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-107709288-A | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| WO-2016046833-A3 | IMPROVED PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016046833-A2 | IMPROVED PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016046833-A2 | IMPROVED PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2016-03-31 | — | — | WO | disclosed |
| CN-1145896-A | New alkoxyaryl compounds, their process of preparation and pharmaceutical compositions which contain them | ADIR (FR) | 1997-03-26 | — | — | CN | disclosed |
| EP-0745583-A1 | Alkoxy aryl compounds with affinity to the melatonine receptors, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-12-04 | — | — | EP | disclosed |
| EP-0708099-A1 | Tricyclic amide compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995029173-A1 | NAPHTHALENE DERIVATIVES, METHOD OF PREPARATION AND USE | GLAXO GROUP LIMITED (GB) | 1995-11-02 | — | — | WO | disclosed |
| EP-0562956-B1 | Naphtylalkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-09-27 | — | — | EP | disclosed |
| US-5420158-A | Melatonin activity | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0562956-A1 | Naphtylalkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-09-29 | — | — | EP | disclosed |