Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.45 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474216 | 0.86 | PGR (0.46) | PGRTDP2MAPTNPC1RAB9A | |
| SCHEMBL27477006 | 0.86 | PGR (0.46) | PGRTDP2MAPTALDH1A1GSK3B | |
| SCHEMBL27479855 | 0.83 | PGR (0.60) | PGRTDP2MAPTNPC1MMP2 | |
| SCHEMBL4172424 | 0.78 | PGR (0.66) | PGRTDP2MAPTRAB9AMMP2 | |
| SCHEMBL27474213 | 0.75 | PGR (0.43) | PGRTDP2MAPTALDH1A1NPC1 | |
| SCHEMBL27494363 | 0.74 | PGR (0.44) | PGRTDP2ALDH1A1NPC1GSK3B | |
| SCHEMBL27491175 | 0.72 | PGR (0.46) | PGRTDP2MAPTALDH1A1NPC1 | |
| SCHEMBL4186117 | 0.67 | PGR (0.47) | PGRTDP2MAPTALDH1A1NPC1 | |
| SCHEMBL6649337 | 0.66 | ALDH1A1 (0.50) | PGRMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11392461 | 0.66 | TSHR (0.73) | PGRMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1172917-C | Steroid receptor modulator compounds and methods | ��λ��ҩ��ɷ�����˾ | 2004-10-27 | — | — | CN | claimed |