Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.96 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.96 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | ACHE | P22303 | 1/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.72 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249630 | 1.00 | KMT2A (0.96) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL13093778 | 0.98 | KMT2A (1.00) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL41833 | 0.98 | KMT2A (1.00) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL4380181 | 0.98 | KMT2A (1.00) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL50599 | 0.98 | KMT2A (1.00) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL28076123 | 0.96 | KMT2A (0.96) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL16653981 | 0.96 | KMT2A (0.96) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL7841850 | 0.93 | KMT2A (0.89) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL3400641 | 0.92 | KMT2A (0.87) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL1895286 | 0.92 | HSD17B10 (0.87) | KMT2ATARDBPHSD17B10CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1208035-A | Dithiolan derivatives, their preparation and their therapeutic effect | SANKYO CO (JP) | 1999-02-17 | — | — | CN | disclosed |