Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | TARDBP | Q13148 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | ACHE | P22303 | 1/20 | 0.74 |
| ▸ | APEX1 | P27695 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.74 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioctic Acid Amide SCHEMBL4380181 | 1.00 | KMT2A (1.00) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL50599 | 1.00 | KMT2A (1.00) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL41833 | 1.00 | KMT2A (1.00) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL27494633 | 0.98 | KMT2A (0.96) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL28076123 | 0.98 | KMT2A (0.96) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL16653981 | 0.98 | KMT2A (0.96) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL29249630 | 0.98 | KMT2A (0.96) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| SCHEMBL7841850 | 0.94 | KMT2A (0.89) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL3400641 | 0.93 | KMT2A (0.87) | KMT2ATARDBPHSD17B10CYP2C9MEN1 | |
| Thioctic Acid Amide SCHEMBL1895286 | 0.93 | HSD17B10 (0.87) | KMT2ATARDBPHSD17B10CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150150770-A1 | METHODS OF TREATING SKIN | TRACIE MARTYN INTERNATIONAL INC (US) | 2015-06-04 | — | — | US | disclosed |
| US-20150150770-A1 | METHODS OF TREATING SKIN | TRACIE MARTYN INTERNATIONAL INC (US) | 2015-06-04 | — | — | US | disclosed |
| US-8933273-B2 | Borate moiety-contained linker and bio-sensing element containing the same | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-01-13 | — | — | US | disclosed |
| US-20140155961-A1 | METHODS OF TREATING SKIN | Tracie Martyn International, Inc. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20140155961-A1 | METHODS OF TREATING SKIN | Tracie Martyn International, Inc. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20100272790-A1 | Methods of Treating Skin | TRACIE MARTYN INTERNATIONAL, LLC (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100272790-A1 | Methods of Treating Skin | TRACIE MARTYN INTERNATIONAL, LLC (US) | 2010-10-28 | — | — | US | disclosed |
| US-7776915-B2 | Topical formulations and methods of use | TRACIE MARTYN INTERNATIONAL, LLC (US) | 2010-08-17 | — | — | US | disclosed |
| US-7776915-B2 | Topical formulations and methods of use | TRACIE MARTYN INTERNATIONAL, LLC (US) | 2010-08-17 | — | — | US | disclosed |
| CN-1208035-A | Dithiolan derivatives, their preparation and their therapeutic effect | SANKYO CO (JP) | 1999-02-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155961-A1 | METHODS OF TREATING SKIN | CUTA, LIPA, DLAT | KMT2A 2256/4885TARDBP 3891/4885HSD17B10 583/4885 |
| US-20100272790-A1 | Methods of Treating Skin | CUTA, LIPA, DLAT | KMT2A 2256/4885TARDBP 3891/4885HSD17B10 583/4885 |
| US-20150150770-A1 | METHODS OF TREATING SKIN | CUTA, LIPA, DLAT | KMT2A 2256/4885TARDBP 3891/4885HSD17B10 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.