Thioctic Acid Amide

Thioctic Acid Amide

SCHEMBL41833

NC(=O)CCCC[C@@H]1CCSS1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
TARDBP Q13148 2/20 1.00
HSD17B10 Q99714 2/20 0.74
CYP2C9 P11712 1/20 0.74
MEN1 O00255 1/20 0.74
NR1I2 O75469 1/20 0.74
ALDH1A1 P00352 1/20 0.74
LMNA P02545 1/20 0.74
POLB P06746 1/20 0.74
THRB P10828 1/20 0.74
TSHR P16473 1/20 0.74
ACHE P22303 1/20 0.74
APEX1 P27695 1/20 0.74
RECQL P46063 1/20 0.74
BLM P54132 1/20 0.74
PMP22 Q01453 1/20 0.74
TDP1 Q9NUW8 1/20 0.74
SAE1 Q9UBE0 1/20 0.74
UBA2 Q9UBT2 1/20 0.74
L3MBTL1 Q9Y468 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioctic Acid Amide SCHEMBL4380181 1.00 KMT2A (1.00) KMT2ATARDBPHSD17B10CYP2C9MEN1
Thioctic Acid Amide SCHEMBL13093778 1.00 KMT2A (1.00) KMT2ATARDBPHSD17B10CYP2C9MEN1
Thioctic Acid Amide SCHEMBL50599 1.00 KMT2A (1.00) KMT2ATARDBPHSD17B10CYP2C9MEN1
SCHEMBL27494633 0.98 KMT2A (0.96) KMT2ATARDBPHSD17B10CYP2C9MEN1
Thioctic Acid Amide SCHEMBL28076123 0.98 KMT2A (0.96) KMT2ATARDBPHSD17B10CYP2C9MEN1
Thioctic Acid Amide SCHEMBL16653981 0.98 KMT2A (0.96) KMT2ATARDBPHSD17B10CYP2C9MEN1
SCHEMBL29249630 0.98 KMT2A (0.96) KMT2ATARDBPHSD17B10CYP2C9MEN1
SCHEMBL7841850 0.94 KMT2A (0.89) KMT2ATARDBPHSD17B10CYP2C9MEN1
Thioctic Acid Amide SCHEMBL3400641 0.93 KMT2A (0.87) KMT2ATARDBPHSD17B10CYP2C9MEN1
Thioctic Acid Amide SCHEMBL1895286 0.93 HSD17B10 (0.87) KMT2ATARDBPHSD17B10CYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10103 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-117462458-B Daily chemical base oil composition and preparation method and application thereof 暨南大学 2026-05-19 CN claimed
CN-122012182-A Method for synthesizing branched fatty acid ester of hydroxy fatty acid by taking natural oil containing hydroxy fatty acid as raw material 江南大学 2026-05-12 CN claimed
CN-118047698-B Preparation method of N- [ (1R) -2- [1,1' -biphenyl ] -4-yl-1- (hydroxymethyl) ethyl ] carbamic acid tert-butyl ester 山东科巢生物制药有限公司 2026-05-12 CN claimed
US-20260034043-A1 NAIL COMPOSITIONS INCLUDING SULFUR-CONTAINING AGENTS AND USES THEREOF LIQWD INC (US) 2026-02-05 US claimed
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
US-12453495-B2 Hormone electrochemical biosensor TRUSTEES OF BOSTON UNIVERSITY (US) 2025-10-28 US claimed
US-12378582-B2 Enzymatic synthesis method of 1-palmitic acid-2-oleic acid-3-triglyceride stearate JIANGNAN UNIVERSITY (CN) 2025-08-05 US claimed
CN-120188827-A Fat composition containing odd-carbon fatty acid and application thereof 丰益(上海)生物技术研发中心有限公司 2025-06-24 CN claimed
WO-2025129192-A1 POLYMER BRUSH COMPOSITIONS INCLUDING CHAIN-END-IMMOBILIZED COFACTORS AND METHODS FOR THE PRODUCTION THEREOF CASCADE BIOCATALYSTS, INC (US) 2025-06-19 WO claimed
US-5182198-A Enzymatic hydrolysis of ester MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-01-26 US claimed
WO-1992013067-A1 PRODUCTION OF ENZYMATICALLY ACTIVE GLUCOCEREBROSIDASE FROM RECOMBINANT CELLS GENZYME CORPORATION (US) 1992-08-06 WO claimed
EP-0327952-B1 SELF-INDICATING AND IMPROVED RESOLUTION ANALYSES EMPLOYING STOICHIOMETRIC CHEMICAL SUBTRACTION MILES INC. (US) 1992-04-15 EP claimed
WO-1991017255-A1 BIODEGRADABLE SUGAR-BASED POLYMER UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1991-11-14 WO claimed
EP-0149339-B1 ASSAY FOR NUCLEIC ACIDS MediSense, Inc. (US) 1989-08-23 EP claimed
EP-0327952-A1 Self-indicating and improved resolution analyses employing stoichiometric chemical subtraction MILES INC. (US) 1989-08-16 EP claimed
EP-0308919-A1 Compositions for topical use having melanin synthesis-inhibiting activity Sansho Seiyaku Co., Ltd. (JP) 1989-03-29 EP claimed
US-4734362-A Process for purifying recombinant proteins, and products thereof CAMBRIDGE BIOSCIENCE CORPORATION (US) 1988-03-29 US claimed
EP-0233044-A2 Process for purifying recombinant proteins, and use of products thereof CAMBRIDGE BIOTECH CORPORATION (US) 1987-08-19 EP claimed
WO-1987004726-A1 PROCESS FOR PURIFYING RECOMBINANT PROTEINS, AND PRODUCTS THEREOF CAMBRIDGE BIOSCIENCE CORPORATION (US) 1987-08-13 WO claimed