Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528376 | 0.98 | SLC6A2 (0.33) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| Hydrochloric Acid SCHEMBL5039030 | 0.96 | SLC6A2 (0.32) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| Hydrochloric Acid SCHEMBL5040217 | 0.96 | SLC6A2 (0.32) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| Bromide SCHEMBL11399424 | 0.83 | SLC6A2 (0.35) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL4798852 | 0.82 | SPHK1 (0.32) | — | |
| SCHEMBL4326261 | 0.80 | NPC1 (0.43) | — | |
| SCHEMBL4239877 | 0.79 | GNAO1 (0.43) | — | |
| SCHEMBL3186641 | 0.79 | SLC6A2 (0.37) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL11685291 | 0.79 | SLC6A2 (0.33) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL4516905 | 0.78 | NPC1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1231466-C | New piperidine derivatives | HOFFMANN LA ROCHE (CH) | 2005-12-14 | — | — | CN | disclosed |
| CN-1468220-A | New piperidine derivatives | - | 2004-01-14 | — | — | CN | disclosed |