Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500593 | 0.86 | TSHR (0.45) | GAALMNATSHRMEN1ALDH1A1 | |
| SCHEMBL7187317 | 0.85 | GAA (0.41) | GAALMNATSHRMEN1ALDH1A1 | |
| SCHEMBL27484256 | 0.85 | LMNA (0.44) | GAALMNAALDH1A1F2RPTGES | |
| SCHEMBL27499972 | 0.84 | GAA (0.46) | GAALMNAKCNK3KCNK9CTNNB1 | |
| SCHEMBL27500286 | 0.84 | CETP (0.42) | GAALMNATSHRF2R | |
| SCHEMBL27561240 | 0.84 | CETP (0.42) | GAALMNATSHRF2R | |
| SCHEMBL27485665 | 0.84 | CETP (0.42) | GAALMNATSHRF2R | |
| SCHEMBL27484267 | 0.82 | ALDH1A1 (0.48) | GAALMNAALDH1A1F2RPTGES | |
| SCHEMBL27486322 | 0.80 | LMNA (0.51) | GAALMNAF2RKCNK3KCNK9 | |
| SCHEMBL7184553 | 0.74 | F2R (0.41) | GAALMNATSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |