Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | S100A9 | P06702 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CCNH | P51946 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566179 | 0.83 | PTGES2 (0.57) | ACLYPFKFB3PTGES2 | |
| SCHEMBL7552185 | 0.79 | ACLY (0.53) | ACLYCYP2C9S100A9TDP1CDK1 | |
| SCHEMBL27498931 | 0.78 | KMT2A (0.43) | ACLY | |
| SCHEMBL27576135 | 0.78 | MCL1 (0.46) | MCL1 | |
| SCHEMBL27535606 | 0.76 | MEN1 (0.54) | CYP2C9MCL1 | |
| SCHEMBL7593518 | 0.76 | ACLY (0.61) | ACLYCYP2C9S100A9TDP1CDK1 | |
| SCHEMBL27575358 | 0.75 | MEN1 (0.45) | ACLYTDP1PTGES2 | |
| SCHEMBL27517617 | 0.75 | PKM (0.47) | PTGES2 | |
| SCHEMBL27516979 | 0.73 | GAA (0.57) | TDP1 | |
| SCHEMBL7589357 | 0.72 | S100A9 (0.57) | ACLYCYP2C9S100A9TDP1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1355697-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1215990-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-05-05 | — | — | CN | disclosed |