Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336583 | 0.84 | CYP19A1 (0.68) | CYP19A1TBXAS1ALDH1A1MEN1KMT2A | |
| SCHEMBL15179017 | 0.84 | CYP19A1 (0.64) | CYP19A1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL7868524 | 0.80 | ALDH1A1 (0.53) | CYP19A1ALDH1A1MAPK1HSD17B10MEN1 | |
| SCHEMBL6992090 | 0.80 | CYP11B1 (0.71) | CYP19A1TBXAS1ALDH1A1MAPK1ALOX15 | |
| SCHEMBL27311222 | 0.76 | CYP19A1 (0.56) | CYP19A1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL15173640 | 0.76 | CYP19A1 (0.56) | CYP19A1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL11607374 | 0.76 | ALDH1A1 (0.57) | CYP19A1TBXAS1ALDH1A1MAPK1ALOX15 | |
| SCHEMBL9414537 | 0.76 | CYP19A1 (0.56) | CYP19A1TBXAS1HRH3CYP11B1CYP11B2 | |
| SCHEMBL10999593 | 0.74 | POLB (0.72) | CYP19A1TBXAS1LMNAKMT2APKM | |
| SCHEMBL30674929 | 0.74 | CYP11B1 (0.58) | CYP19A1TBXAS1ALDH1A1MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1033586-C | Imidazo [2, 1-b ] [3] benzazepine derivatives and their use as anti-inflammatory agents | JANSSEN PHARMACEUTICA NV (BE) | 1996-12-18 | — | — | CN | disclosed |