Thiophene

Thiophene

SCHEMBL27503161

CCCCC(=O)CC1CCCC1.c1ccsc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
NAAA Q02083 2/20 0.34
EPHX2 P34913 2/20 0.33
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
NPC1 O15118 3/20 0.31
RAB9A P51151 2/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
P2RX7 Q99572 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
IAPP P10997 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL27502823 0.98 CYP1A2 (0.38) CYP1A2NAAAEPHX2KMT2ANPC1
Thiophene SCHEMBL27522807 0.95 NAAA (0.40) CYP1A2NAAAMAPTKMT2ACES2
Thiophene SCHEMBL27504244 0.94 NAAA (0.41) CYP1A2NAAAEPHX2MEN1MAPT
SCHEMBL13485707 0.87 CYP1A2 (0.45) CYP1A2NAAAMEN1POLBMAPT
SCHEMBL787945 0.85 CYP1A2 (0.48) CYP1A2NAAAEPHX2MEN1POLB
Thiophene SCHEMBL27503885 0.83 EPHX2 (0.36) EPHX2MEN1KMT2ANPC1RAB9A
Thiophene SCHEMBL27537280 0.82 EPHX2 (0.38) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL11625205 0.78 NAAA (0.53) CYP1A2NAAAEPHX2MAPTKMT2A
SCHEMBL2990381 0.78 NAAA (0.53) CYP1A2NAAAEPHX2MAPTKMT2A
SCHEMBL19508699 0.78 NAAA (0.53) CYP1A2NAAAEPHX2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1229693-C Optical enhancement right photoetching rubber composite and sulfonium salt SUMITOMO CHEMICAL CO (JP) 2005-11-30 CN disclosed