SCHEMBL2990381

SCHEMBL2990381

CCCCCCCCCCCC(=O)CC1CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.53
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.45
CES2 O00748 3/20 0.43
CES1 P23141 3/20 0.43
HAO1 Q9UJM8 1/20 0.43
EPHX1 P07099 6/20 0.42
EPHX2 P34913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19508699 1.00 NAAA (0.53) NAAAMAPTKMT2ACYP1A2CES2
SCHEMBL11625205 1.00 NAAA (0.53) NAAAMAPTKMT2ACYP1A2CES2
SCHEMBL28042801 0.92 KMT2A (0.45) NAAAMAPTKMT2ACES2CES1
SCHEMBL787945 0.92 CYP1A2 (0.48) NAAAMAPTKMT2ACYP1A2CES2
SCHEMBL13485707 0.90 CYP1A2 (0.45) NAAAMAPTKMT2ACYP1A2CES2
SCHEMBL9978409 0.88 KMT2A (0.48) NAAAMAPTKMT2ACES2CES1
Thiophene SCHEMBL27504244 0.86 NAAA (0.41) NAAAMAPTKMT2ACYP1A2EPHX1
Thiophene SCHEMBL27522807 0.84 NAAA (0.40) NAAAMAPTKMT2ACYP1A2CES2
SCHEMBL12988441 0.84 CYP1A2 (0.46) NAAACYP1A2
SCHEMBL10747739 0.84 CYP1A2 (0.59) NAAAMAPTKMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed