Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28412112 | 0.72 | BACE1 (0.40) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL14039627 | 0.70 | CHRM2 (0.43) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL15571396 | 0.68 | ALDH1A1 (0.39) | GRIN1GRIN2ALMNAHTTCHRM2 | |
| SCHEMBL27721335 | 0.67 | GRIN1 (0.44) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL23269499 | 0.66 | CHRM2 (0.43) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL16409353 | 0.65 | CHRM2 (0.57) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL28843857 | 0.64 | GRIN1 (0.36) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL10417243 | 0.64 | AKR1C1 (0.46) | LMNAHTTCHRM3ATMPPME1 | |
| SCHEMBL28266321 | 0.63 | CHRM2 (0.40) | GRIN1GRIN2ACHRM2CHRM4CHRM5 | |
| SCHEMBL30877933 | 0.63 | AKR1C1 (0.46) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1196694-C | Polymerizable, photoactive 1, 3-dioxolane diesters | ROLIC AG (CH) | 2005-04-13 | — | — | CN | disclosed |
| CN-1258291-A | Polymerizable, photoactive 1, 3-dioxolane diesters | ROLIC AG (CH) | 2000-06-28 | — | — | CN | disclosed |