SCHEMBL28412112

SCHEMBL28412112

O=C1COC(c2ccccc2)(C2CCCCC2)OC1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.40
BACE2 Q9Y5Z0 2/20 0.40
APP P05067 1/20 0.40
CTSD P07339 1/20 0.40
L3MBTL1 Q9Y468 4/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
RECQL P46063 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 1/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14039627 0.78 CHRM2 (0.43) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL15571396 0.77 ALDH1A1 (0.39) ALDH1A1GRIN1GRIN2ACHRM2CHRM4
SCHEMBL27504305 0.72 GRIN1 (0.39) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL16409353 0.69 CHRM2 (0.57) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL27721335 0.68 GRIN1 (0.44) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL7777523 0.68 L3MBTL1 (0.45) BACE1BACE2APPCTSDL3MBTL1
SCHEMBL1690206 0.67 CHRM2 (0.55) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL19308438 0.67 CHRM2 (0.55) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL28843857 0.65 GRIN1 (0.36) GRIN1GRIN2ACHRM2CHRM4CHRM5
SCHEMBL28266321 0.65 CHRM2 (0.40) BACE1BACE2APPCTSDGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233817-B Oxidation method of glycerol acetal derivative 中国科学院大连化学物理研究所 2023-01-17 CN disclosed
CN-111233817-A Oxidation method of glycerol acetal derivative 中国科学院大连化学物理研究所 2020-06-05 CN disclosed