Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27504375 | 0.71 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL4561816 | 0.68 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL2760501 | 0.68 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL1520665 | 0.67 | L3MBTL1 (0.64) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL6305517 | 0.65 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL13187360 | 0.61 | KMT2A (0.60) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL28848233 | 0.61 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL29091846 | 0.60 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL8280386 | 0.60 | MAPT (0.46) | ALDH1A1L3MBTL1ATMKMT2AMEN1 | |
| SCHEMBL20568978 | 0.59 | F2 (0.39) | ALDH1A1KMT2AMEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1244576-C | Compound (I) | ASTRAZENECA AB (SE) | 2006-03-08 | — | — | CN | disclosed |
| CN-1660839-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-08-31 | — | — | CN | disclosed |
| CN-1433411-A | Compound (I) | ASTRAZENECA AB (SE) | 2003-07-30 | — | — | CN | disclosed |