SCHEMBL27504451

SCHEMBL27504451

Oc1ccc(C2Cc3cccc4cccc2c34)cc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
AR P10275 1/20 0.42
IDE P14735 1/20 0.42
KMT2A Q03164 1/20 0.42
MTNR1A P48039 8/20 0.41
MTNR1B P49286 8/20 0.41
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
ESR2 Q92731 3/20 0.38
ESR1 P03372 2/20 0.38
FGFR1 P11362 1/20 0.35
FGFR2 P21802 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27455448 1.00 MEN1 (0.42) MEN1GAAARIDEKMT2A
SCHEMBL27544980 1.00 MEN1 (0.42) MEN1GAAARIDEKMT2A
SCHEMBL28371568 0.91 MTNR1A (0.43) MEN1KMT2AMTNR1AMTNR1BADRA2A
SCHEMBL5374308 0.84 FGFR1 (0.47) MEN1KMT2AMTNR1AMTNR1BADRA2A
SCHEMBL28279325 0.84 MTNR1A (0.40) MTNR1AMTNR1BADRA2AADRA2BADRA2C
SCHEMBL27854943 0.83 SLC6A2 (0.43) MEN1KMT2AMTNR1AMTNR1BADRA2A
SCHEMBL27690916 0.81 MTNR1A (0.40) MTNR1AMTNR1BADRA2AADRA2BADRA2C
SCHEMBL4915638 0.80 MTNR1A (0.38) MTNR1AMTNR1BADRA2AADRA2BADRA2C
SCHEMBL27903771 0.80 MTNR1A (0.36) MTNR1AMTNR1BADRA2AADRA2BADRA2C
Acenaphthene SCHEMBL28276761 0.79 ADRA2A (0.43) MEN1KMT2AMTNR1AMTNR1BADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107090191-B A kind of rhodamine fluorescent dyes and preparation method thereof 许昌学院 2018-12-11 CN claimed
CN-107141303-A A kind of response type sulfhydryl compound probe and preparation method thereof 许昌学院 2017-09-08 CN claimed
CN-107090191-A One class rhodamine fluorescent dyes and preparation method thereof 许昌学院 2017-08-25 CN claimed
CN-106995451-A A kind of response type cysteine probe and preparation method thereof 许昌学院 2017-08-01 CN claimed
CN-107141303-B A kind of response type sulfhydryl compound probe and preparation method thereof 许昌学院 2019-03-15 CN disclosed
CN-106995451-B A kind of response type cysteine probe and preparation method thereof 许昌学院 2019-03-15 CN disclosed
CN-107090191-B A kind of rhodamine fluorescent dyes and preparation method thereof 许昌学院 2018-12-11 CN disclosed
CN-107141303-A A kind of response type sulfhydryl compound probe and preparation method thereof 许昌学院 2017-09-08 CN disclosed
CN-107090191-A One class rhodamine fluorescent dyes and preparation method thereof 许昌学院 2017-08-25 CN disclosed
CN-106995451-A A kind of response type cysteine probe and preparation method thereof 许昌学院 2017-08-01 CN disclosed
CN-101679623-B Polycarbonate resin and method for producing the same MITSUBISHI GAS CHEMICAL CO.,INC. (JP) 2011-12-21 CN disclosed
CN-101186562-B Low energy-consumption, high conversion and selectivity fast synthesis method for aryl methyl ether UNIV DALIAN TECH 2010-06-02 CN disclosed
CN-101679623-A Polycarbonate resin and method for producing the same MITSUBISHI GAS CHEMICAL CO 2010-03-24 CN disclosed
CN-101186562-A Low energy-consumption high conversion and selectivity fast synthesis method for aryl methyl ether UNIV DALIAN TECH (CN) 2008-05-28 CN disclosed
CN-1853141-A Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2006-10-25 CN disclosed
CN-1231519-C Modified polyphenylene ether resin ASAHI CHEMICAL IND (JP) 2005-12-14 CN disclosed
CN-1425033-A Modified polyphenylene ether resin ASAHI CHEMICAL IND (JP) 2003-06-18 CN disclosed