Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31668450 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL9746269 | 0.85 | POLB (0.68) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL3088444 | 0.83 | MAPT (0.50) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL16009974 | 0.81 | POLB (0.48) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL1075595 | 0.81 | POLB (0.48) | ALDH1A1MEN1KMT2AHTTPOLB | |
| Hydrochloric Acid SCHEMBL28531727 | 0.81 | MAPT (0.49) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL28208533 | 0.81 | POLB (0.48) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL13814102 | 0.80 | MAPT (0.48) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL29202666 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL1180653 | 0.79 | POLB (0.64) | ALDH1A1MEN1KMT2AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882527-A | Biphenyloxy-acids | WYETH CORP (US) | 2006-12-20 | — | — | CN | disclosed |
| CN-1197860-C | FAB I inhibitors | SMITHKLINE BEECHAM CORP (CA) | 2005-04-20 | — | — | CN | disclosed |
| CN-1378542-A | Antigen binding fragment I inhibitors | SMITHKLINE BEECHAM CORP (US) | 2002-11-06 | — | — | CN | disclosed |