Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359288 | 0.82 | SLC6A2 (0.45) | CYP2D6SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL28112889 | 0.80 | ADRB2 (0.49) | CYP2D6SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL7366527 | 0.77 | L3MBTL1 (0.63) | CYP2D6SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL7359408 | 0.75 | CYP2D6 (0.45) | CYP2D6SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL24028036 | 0.74 | SLC6A2 (0.43) | CYP2D6SLC6A2SLC6A4SLC6A3RAD52 | |
| SCHEMBL7358923 | 0.74 | CYP2D6 (0.41) | CYP2D6SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL6204295 | 0.73 | CYP2D6 (0.43) | CYP2D6SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7365020 | 0.73 | CYP2D6 (0.41) | CYP2D6SLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL9382691 | 0.71 | SLC6A2 (0.47) | CYP2D6SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL38662188 | 0.71 | SLC6A2 (0.43) | CYP2D6SLC6A2SLC6A4SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1120334-A | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | CN | disclosed |