SCHEMBL2750495

SCHEMBL2750495

Nc1ccon1.O=C1NCCO1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.34
FABP6 P51161 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6508296 0.80 PDE3B (0.31) HSP90AA1FABP6
Methylamine SCHEMBL27885237 0.75
Hydrazine SCHEMBL28115277 0.73
SCHEMBL73803 0.73
SCHEMBL4621927 0.73 FABP6 (0.35) HSP90AA1FABP6
SCHEMBL80643 0.73
SCHEMBL4198 0.73
SCHEMBL969300 0.73
Fluoride SCHEMBL27461973 0.73
SCHEMBL28445159 0.72 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178683-B2 Antimicrobial ortho-fluorophenyl oxazolidinones for treatment of bacterial infections MICURX PHARMACEUTICALS, INC. (KY) 2012-05-15 US disclosed
EP-2185549-A1 ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS Micurx Pharmaceuticals, Inc. (KY) 2010-05-19 EP disclosed
US-20090048305-A1 Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) 2009-02-19 US disclosed
WO-2009020616-A1 ANTIMICROBIAL ORTHO-FLUOROPHENYL OXAZOLIDINONES FOR TREATMENT OF BACTERIAL INFECTIONS MICURX PHARMACEUTICALS, INC. (KY) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048305-A1 Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections OXA1L, OGFOD1, OLA1 HSP90AA1 1650/4885FABP6 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.