Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CASR | P41180 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7265962 | 0.88 | KMT2A (0.46) | CA12CA7CA9CA14APAF1 | |
| SCHEMBL6551973 | 0.85 | CA12 (0.40) | CA12CA7CA9CA14CYP2D6 | |
| SCHEMBL27551142 | 0.85 | L3MBTL1 (0.54) | APAF1CYP3A4CASRCHRM2HTR1A | |
| SCHEMBL27570822 | 0.85 | L3MBTL1 (0.54) | APAF1CYP3A4CASRCHRM2HTR1A | |
| SCHEMBL19193984 | 0.85 | L3MBTL1 (0.54) | APAF1CYP3A4CASRCHRM2HTR1A | |
| SCHEMBL23135630 | 0.84 | CA12 (0.65) | CA12CA7CA9CA14APAF1 | |
| SCHEMBL2750779 | 0.84 | CA12 (0.65) | CA12CA7CA9CA14APAF1 | |
| SCHEMBL2276846 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CTSK | |
| SCHEMBL4709711 | 0.81 | MALT1 (0.51) | APAF1CYP3A4CASRCHRM2HTR1A | |
| SCHEMBL4705684 | 0.81 | MALT1 (0.51) | APAF1CYP3A4CASRCHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102707-A2 | SUBSTITUTED OXAZAPHOSPHORINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009102707-A2 | SUBSTITUTED OXAZAPHOSPHORINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090202540-A1 | SUBSTITUTED OXAZAPHOSPHORINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090202540-A1 | SUBSTITUTED OXAZAPHOSPHORINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090202540-A1 | SUBSTITUTED OXAZAPHOSPHORINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202540-A1 | SUBSTITUTED OXAZAPHOSPHORINES | TYMP, PAICS, CD47 | CA12 619/4885CA7 1394/4885CA9 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.