Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL27609877 | 1.00 | LMNA (0.43) | LMNAKDM4EGPR3CYP3A4CDK4 | |
| Benzimidazole SCHEMBL17157220 | 0.85 | KDM4E (0.47) | LMNAKDM4EGPR3CYP3A4MAPT | |
| SCHEMBL982910 | 0.85 | LMNA (0.58) | LMNAKDM4EGPR3CYP3A4MAPT | |
| SCHEMBL29687953 | 0.85 | LMNA (0.58) | LMNAKDM4EGPR3CYP3A4MAPT | |
| Benzimidazole SCHEMBL29245695 | 0.85 | GABRA1 (0.39) | LMNAKDM4EGPR3CDK4CCND1 | |
| Benzimidazole SCHEMBL28369063 | 0.85 | GABRA1 (0.39) | LMNAKDM4EGPR3CDK4CCND1 | |
| SCHEMBL28399164 | 0.84 | LMNA (0.56) | LMNAKDM4EGPR3CYP3A4MAPT | |
| Benzimidazole SCHEMBL28374782 | 0.83 | LMNA (0.66) | LMNAKDM4ECYP3A4MAPTSMN1; SMN2 | |
| 1-Naphthoquinoline SCHEMBL9437431 | 0.83 | LMNA (0.51) | LMNAKDM4ECYP3A4MAPTSMN1; SMN2 | |
| Phenanthroline SCHEMBL27929131 | 0.82 | LMNA (0.55) | LMNAKDM4ECYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1155597-A | Fabrics comprising blended yarns and blending process, finishing process and the use thereof | HOECHST TREVIRA GMBH & CO KG (DE) | 1997-07-30 | — | — | CN | disclosed |